Rovers Under-23s take on Everton Under-23s this afternoon with a place in the next round of the Lancashire Senior Cup at stake for the winners.
Rovers are the holders of the competition and will hope to go one step further to reclaiming their crown by beating David Unsworth's side at the Rovers Academy later today, kick-off being 1pm.
In terms of team news, Jacob Davenport is expected to be part of the team as he continues to get match fitness under his belt.
But fellow first teamer Sam Hart is still out with a knee injury, which means Lewis Thompson is likely to continue on the left side of the back four.
Another absentee is expected to be Dominic Samuel, whilst Brad Lyons could miss out again following a recent injury that kept him out of the recent games at Southampton and Liverpool.
It remains to be seen whether Ben Brereton will be involved, with the forward missing a large chunk of the season so far after picking up a knee injury.
Jack Vale is likely to play a part, as is Dan Butterworth, who returned with a first half brace at Southampton prior to playing more than 70 minutes against Liverpool at the weekend.
Everton won the title last season and are currently unbeaten in the league this term after four games played.
Frontman Anthony Gordon has been key to Everton's decent start to the current campaign under Unsworth, with the frontman finding the net on five occasions so far this term.
The Toffees have suffered defeats in their last two games in league and cup, with Derby County earning a big 4-1 home win against them last time out.
Rovers beat Accrington in the last round to reach this stage of the competition, with Dominic Samuel and Danny Graham scoring a penalty each to earn a comfortable 2-0 win at Leyland.
Everton squeezed past Blackpool in their first game of the competition, sneaking a 4-3 away win against The Tangerines last month.
The quarter-final draw in full is as follows:
Rovers v Everton
Burnley v AFC Fylde
Preston North End v Barrow
Morecambe v Bolton Wanderers or Wigan Athletic
Supporters are welcome to attend, with the game being free of charge.