Young Development Squad pair Jack Vale and Lewis Thompson are both expected to play for their respective countries this evening.
Vale's in the squad for Wales Under-21s' home game against Bosnia & Herzegovina U21s really needing a win, with the last outing - a defeat in Moldova last month - leaving Paul Bodin's side bottom of Group I with just three points from the opening three games.
Kick-off later today is at 4pm, with the tie to be played at the Racecourse Ground in Vale's hometown of Wrexham.
"We need to put that right and put on a better performance against Bosnia," Bodin said.
"The most disappointing was the performance really, we didn't play as well as we can."
"We started the campaign really well with a great positive performance against Belgium. The Germans were a different kettle of fish, they're very strong."
Elsewhere, Thompson and Northern Ireland's Under-21s are in a similar predicament in Group H.
The Ballymena Showgrounds plays host to the team for the showdown against Romania's Under-21s, kick-off 5.30pm, with Thompson hoping to feature after coming off the bench on Thursday in the friendly against Hungary Under-21s.
But despite his team's position in the group, boss Ian Baraclough has revealed that he still has plenty of belief in his young squad.
"We've had three tough away games and I was disappointed not to have come away from top seeds Denmark with at least a point," he told the Irish FA website.
"However, I see Romania at home as a good chance to start getting points on the board once again. I have no doubt it's a game we can win.
"Romania are a strong side and have made a good start to the group but if we can take our chances in the game we can come away with the three points."
Only the group winners and the best runners-up qualify automatically for the finals in Hungary and Slovenia.
The other eight group runners-up will secure a play-off spot with four further teams qualifying for the finals.
Good luck, lads!