Tony Mowbray says Charlie Mulgrew and Bradley Dack will be assessed ahead of Tuesday night's home clash against Derby County.
Mulgrew limped off at half time after seemingly picking up an injury when tackling Benik Afobe just before the interval in the 1-0 defeat to Stoke City.
Elsewhere, Dack wasn't invoved in the squad against the Potters, with Mowbray revealing that the 25-year-old has a slight hamstring issue.
“Charlie’s damaged his ankle I think in a challenge," the boss said to iFollow Rovers after the game.
“He wanted to stay on, but I didn’t want a player out there playing less than 100%.
“Every player in our team needs to be playing at 100% and I felt Derrick Williams playing at left centre half is better than a 75% fit Charlie Mulgrew, so I took that decision out of his hands.
“Let’s wait and see how Charlie is tomorrow in training."
And on Dack, the boss is hopeful the playmaker will recover in time for Tuesday's encounter against the Rams at Ewood Park.
“Bradley walked off training on Thursday feeling his hamstring," Mowbray added.
"Experience tells me that he can’t say his hamstring is 100% only two days later.
“We wanted to give him some treatment and time to make sure that the first time he sprints in a game he doesn't pull up and misses the rest of the season.
“We shouldn’t risk him and that was what we went for."