Two changes from the XI that started against Bristol Rovers at the weekend as Rovers aim for four wins on the spin.
Coming in for Rovers at Bloomfield Road are one-time Blackpool loanee Danny Graham - who impressed off the bench on Saturday - and Elliott Bennett - another to have started as a substitute on the day.
Swapping places with the duo are Joe Nuttall and Corry Evans, who can both be utilised off the bench for Tony Mowbray if required.
Peter Whittingham makes his 500th career league appearance this evening.
The hosts - managed by former Ewood boss Gary Bowyer - include ex-Rovers pair Nathan Delfouneso and Jay Spearing in their XI, whilst another former Blackburn youth graduate in Andy Taylor starts on the bench.
Blackpool: Allsop, Mellor, Aimson, Anderton, Ryan (c), Longstaff, Solomon-Otebor, Turton, Daniel, Delfouneso, Spearing.
Substitutes: Williams, Taylor, D'Almeida, Gnanduillet, Philliskirk, Menga, Cooke
Rovers: Raya, Nyambe, Downing, Mulgrew (c), Williams, Smallwood, Whittingham, Bennett, Dack, Antonsson, Graham.
Substitutes: Leutwiler, Ward, Caddis, Evans, Harper, Nuttall, Samuel