Rovers boss Tony Mowbray is confident Charlie Mulgrew and Darragh Lenihan will be fit to face Southend in next Saturday's League One opener.
The central defensive duo sat out Friday's final pre-season friendly at Carlisle, but the boss expects them to return to training this week.
Speaking after 3-1 defeat at Brunton Park, Mowbray side: "They're both carrying little knocks. We left them at home, we didn't bring them.
"It's important that they get themselves ready to train hopefully early in the week and we'll see if they're ready for the weekend. Fingers crossed they will be.
"I think they're important footballers for the club, not just their abilities, but their leadership qualities on the pitch and sometimes you need a team that has a desire not to lose.
"We had some good footballers on the pitch tonight in the defensive side of the team, but they probably don't have the leadership qualities of the players that were missing."
Ben Gladwin also missed the trip to Cumbria with a minor niggle and Mowbray added: "Ben's carrying a knock as well. He was just a bit tight.
"I don't see any problems there, it was just a decision that was made that we don't need to bring them if they've got any issues at all.
"I think they probably would have all played if it had been a league game, but we don't need to risk anybody."