Paul Lambert has made three changes from the side that defeated MK Dons on Saturday.
With Corry Evans missing out through injury, Hope Akpan comes in to replace him, whilst Matt Grimes and Tony Watt get the nod ahead of Elliott Bennett and Chris Brown.
The visitors make two changes from their weekend win as George Friend and former Rover Jordan Rhodes replace Emilio Nsue and Gaston Ramirez.
ROVERS: Steele, Marshall, Duffy, Hanley (c), Spurr, J. Gomez, Lenihan, Akpan, Grimes, Watt, Graham.
Subs: Raya (GK), Henley, Brown, Ward, Bennett, Conway, Jackson.
MIDDLESBROUGH: Konstantopoulos, Leadbitter (c), de Laet, Adomah, Friend, Forshaw, Fry, Nugent, Gibson, Rhodes, Downing.
Subs: Mejias (GK), Clayton, De Pena, Stuani, Ramirez, Nsue, Kalas.