Rovers have handed debut starts to Tony Watt and Elliott Ward for this afternoon's Emirates FA Cup fourth round clash.
The pair are part of six changes from the side that drew at Charlton seven days ago as Ben Marshall, Darragh Lenihan, and Elliott Bennett return.
There's also a first start for January signing Simeon Jackson. Hope Akpan misses out with a sore knee picked up in training yesterday.
The U's make one change from the side that defeated Portsmouth last time out as Jordan Bowery makes his full debut, he comes in for Danny Hylton.
OXFORD: Slocombe, Baldock, Skarz, Roofe, Mullins, Wright, Sercombe, MacDonald, O'Dowda, Lundstram, Bowery.
Subs: Buchel (GK), Hylton, Ruffles, Kenny, Ashby, Dunkley, Evans.
ROVERS: Steele, Marshall, Ward, Hanley (c), Spurr, Bennett, Lenihan, Evans, Conway, Jackson, Watt.
Subs: Raya (GK), Henley, Kilgallon, Lawrence, Taylor, Duffy.