Rovers make two changes from the side that knocked Mansfield out of the EFL Cup on Tuesday night.
Adam Henley and Liam Feeney return to the starting XI, with Stephen Hendrie and Craig Conway dropping to the bench. New signing Sam Gallagher is named amongst the substitutes.
Jason Lowe captains the side on his 150th appearance.
The hosts make six changes from their midweek loss to Oldham, with Adam Bogdan, Alex Gilbey, Dan Burn, Nick Powell, Yanic Wildschut, and Luke Burke coming into the side.
WIGAN: Bogdan, Gilbey, Burn, Powell, Grigg, Wildschut, Power, Warnock, Morgan (c), Burke, Perkins.
Subs: Jaaskelainen (GK), Jacobs, Davies, Flores, Hendry, Colclough, Chow.
ROVERS: Steele, Lowe (c), Duffy, Greer, Henley, Feeney, Lenihan, Byrne, Marshall, Stokes, Graham.
Subs: Raya (GK), Gallagher, Hendrie, Akpan, Guthrie, Conway, Wharton.