Rovers have made seven changes changes from the side that progressed through to the third round of the EFL Cup on Tuesday night.
There are debuts for Friday signings Tommie Hoban and Derrick Williams, whilst Jason Steele, Gordon Greer, Ben Marshall, Danny Graham and Danny Guthrie all come into the starting line-up.
Fulham, who were also victorious in midweek, have former Rover Tom Cairney in from the start whilst Ryan Tunnicliffe is named amongst the substitutes.
ROVERS: Steele, Lowe, Hoban, Greer, Williams, Marshall, Guthrie, Akpan, Conway, Gallagher, Graham.
Subs: Raya (GK), Feeney, Byrne, Stokes, Samuelsen, Lenihan, Wharton.
FULHAM: Button, Odoi, McDonald, Kabano, Parker (c), Smith, Cairney, Madl, Aluko, Kalas, Sessegnon.
Subs: Bettinelli (GK), Malone, Readm, Woodrow, Tunnicliffe, Christensen, Jozabed.