Rovers make four changes from the side that drew with Burton Albion at the weekend.
Into the side come David Raya, Liam Feeney, Anthony Stokes and Shane Duffy for the EFL Cup 2nd round tie against the Railwaymen. Jason Steele, Gordon Greer, Ben Marshall and Danny Graham all dropping to the bench.
For the visitors, they make two changes from their draw with Newport County on Saturday as Callum Saunders and Danny Hollands come in for Ryan Lowe and James Jones.
ROVERS: Raya, Lowe (c), Duffy, Wharton, Hendrie, Feeney, Byrne, Akpan, Conway, Stokes, Gallagher.
Subs: Steele (GK), Greer, Marshall, Graham, Guthrie, Mahoney, Doyle.
CREWE: Garratt, Turton, Guthrie, Davis, Dagnall (c), Saunders, Cooper, Bakayogo, Hollands, Bingham, Kiwomya.
Subs: Richards (GK), Ray, Nugent, Lowe, Jones, Kirk, Ainley.