Paul Lambert has made two changes from the side that defeated Brentford a fortnight ago.
With Grant Hanley serving a one-match ban following his sending off at Griffin Park, his place in the heart of the Rovers defence is taken by Elliott Ward.
The other change is further forward with Tony Watt returning up front at the expense of Craig Conway who drops to the bench.
The visitors also make two changes from the side that drew with Queens Park Rangers as Joe Garner and Alan Browne replace Daniel Johnson and Callum Robinson.
ROVERS: Steele, Marshall, Ward, Duffy (c), Spurr, Akpan, Lenihan, J. Gomez, Bennett, Watt, Graham.
Subs: Raya (GK), Henley, Kilgallon, Brown, Grimes, Conway, Jackson.
PRESTON: Lindegaard, Cunningham, Pearson, Clarke (c), Wright, Gallagher, Garner, Woods, Browne, Hugill, Reach.
Subs: Kirkland (GK), Vermijl, Beckford, Johnson, Doyle, Huntington, Robinson