Rovers' also have experience in their ranks with Markus Olsson and Yann Songo'o getting a runout but the United trio will surely provide a stern test for Eric Kinder's young side.
The Rovers development squad go into this evening's match in good heart after a 3-1 win over Hull City in the Under-21 Premier League Cup. Goalscorers on the night, Jordan Preston, Jordan Slew and Hugo Fernandez all feature once more.
John O'Sullivan is back after international duty, whilst Matty Urwin, on loan with Stalybridge Celtic, gets his opportunity in goal.
ROVERS: Urwin, Fernandez, Olsson, Lenihan, Daly, Songo'o, Slew, O'Sullivan, Preston, Payne, R. Hanley.
Subs: Rittenberg, Raya (GK), Bauress, Cotton, Haley.
MAN UTD: Johnstone, Varela, James, Rothwell, Ekangamene, Thorpe, Janko, Fletcher, Wilson, Fabio, Zaha.
Subs: Pearson, Gollini (GK), Pereira, Love, Rudge, Barmby.
Kick-off at Leigh Sports Village is at 7.00pm. Rovers season ticket holders can gain free admission on production of their season ticket card. General admission prices are £4 Adults, £2 Concessions.