Rovers return to Ewood Park following almost three weeks without a home game, with Huddersfield Town the visitors for the Championship encounter.
Following relegation from the Premier League last term, The Terriers initially struggled at the beginning of this campaign, but have picked up in recent weeks following the appointment of Danny Cowley as boss.
Cowley, alongside brother and assistant manager Nicky, arrived at The John Smith's Stadium last month after a compensation package was agreed with League One side Lincoln City.
The Yorkshiremen arrive at Ewood on the back of a three-game unbeaten run, which includes back-to-back victories at Stoke City and at home to Hull City, keeping clean sheets in both matches.
The recent record between the two sides has seen five draws from the last six clashes, with Rovers looking to bounce back from the defeat to Queens Park Rangers before the international break.
Tony Mowbray will be without defensive duo Darragh Lenihan and Greg Cunningham through injury, with the latter expected to be out for the rest of the campaign due to a tear of his anterior cruciate ligament.
Lenihan will be back sooner than his Irish compatriot, but will be missing for a number of weeks.
That means that Tosin Adarabioyo is likely to step in at the heart of the Rovers defence, with Amari'i Bell expected to take Cunningham's vacant left back slot.
Bell could make his 50th start in blue-and-white since arriving from Fleetwood Town in January 2018, whilst Stewart Downing could appear in the league for the 550th time of his career.
Ahead of the game, Cowley is anticipating a 'really tough game' against Mowbray's men.
"We've been working over the last couple of weeks on our organisation both in and out of possession," the Town boss said to Huddersfield's official YouTube channel.
"Rovers are a really good team. Tony Mowbray and Mark Venus (assistant manager) have done a really good job there over a prolonged period of time.
"They've been together so long and have developed a really good squad with quality and depth and with good characters.
"They have the ability to go quick if they want to to Danny Graham or Sam Gallagher. They have good players who can break the lines and carry threats," he added.
"We're anticipating a really tough game when Saturday comes around."
A reminder that kick-off tomorrow is at the earlier time of 12.30pm and you can track all the action with an audio pass on iFollow Rovers and our social media channels.