The 20-year-old centre back will link up with the League One club until December 29th.
Edwards, who has come through the youth ranks at Rovers and captained the Under-18s to the final of the FA Youth Cup in 2011-12, spent time on loan with League Two promotion chasers Chesterfield at the start of the current campaign, making seven appearances.
He got his first taste of league football last season, enjoying two successful spells with Rochdale and Fleetwood Town.
Edwards has been given permission to play for Tranmere in the FA Cup. Ronnie Moore’s side travel to Peterborough in the second round on Saturday December 7th.