Following tonight's match against Wanderers Rovers travel to the capital to take on Millwall on Sunday in the quarter-finals of the FA Cup with Budweiser before two local home derbies against Burnley and Blackpool.
But Appleton insists that Rovers can't be sidetracked by future fixtures, applying the old adage of taking one game at a time.
"If any of them are thinking about Millwall, they won't be playing against Millwall," said Appleton.
"If anyone knows me by now, and knows what I'm about they'll know that the next game is the most important and that one is Bolton."
Tonight's match starts a run of three league games against three local rivals with Appleton believing that these are games to savour.
"I wish I was still playing as these are the kind of games that you love to be involved in," added the Rovers boss.
"They'll be full throttle, there's going to be a lot of tackles going in on the day, a lot of emotion in the stands, they are games we should all look forward to really.
"When you win those type of games, even though you don't get more than three points for winning them it feels like ten points because of the games they are."
Tickets for this evening's match at Bolton will be on sale cash only from the away turnstiles from 7pm. Supporters should note that numbers are very limited. Prices are £15 for Adults, £5 for Seniors and Under-21s.