The Rovers boss was just a youth coach at the Rams' Academy when Steve McClaren was assistant to County manager Jim Smith.
Since returning to Pride Park back in September, former England manager McClaren has overseen the Championship club's rise up the table with 11 wins from his 16 games in charge. And for Bowyer, it is no surprise to him to see McClaren do so well.
"I was the Under-12 coach at Derby when he was the assistant manager," said Bowyer.
"His lad used to play for the Under-11s so he used to come on a Sunday and we used to see him stood on the touchline.
"Then he was assistant manager to Jim Smith, he was very highly thought of and so it was proved with his career going on as it has.
"He's now gone back to Derby and has done fantastically well there."
The match against the Rams will prove to be another tough test for Bowyer's young side but the boss sees it as an opportunity to go back on another unbeaten run.
"Every game is big, I know that it is a cliche but it is," said the manager. "You've only got to look at the results every week on a Saturday, there is no given game, there is no certainties, everybody can beat everybody.
"Sometimes the league position just brings people into a false sense of expectation.
"I think every game that you play in the Championship that you play is a test. There are no certainties and there is no easy game and Saturday is going to be exactly that.
"They have a fantastic coach in Steve McClaren, they've had a good run and it is a run that we would love to go on ourselves. The match provides us with an opportunity to start on Saturday."
Tickets for Saturday's match are on open sale and will be available up to the 3.00pm kick-off. Prices are from £19 for Adults, £12 Seniors and £7 Students.