Lee Williamson, Corry Evans and Adam Henley could all be back in the squad for the trip to the north east, but Josh King is set for a spell on the sidelines.
Williamson missed the weekend win over Blackpool due to concussion sustained against Barnsley, but has shown no after effects in training and is back in the squad, whilst Adam Henley (achilles) and Corry Evans (ankle) are also closing in on a return.
Speaking on Thursday, manager Gary Bowyer said: "It has been a good week as one or two recovered from knocks and bumps and we've been able to concentrate on the football.
"Lee Williamson has trained well all week so he comes back into the squad.
"Corry Evans has been with us all week so we are hoping that if he doesn't feature this weekend then he certainly will do on Monday night with the Under-21s.
"We'll assess Adam Henley in the morning, he's had a scan and it has come back better than we had hoped, so we'll see how he does in training tomorrow, and Dickson Etuhu is not too far away, he is still doing his rehab."
However that good news is tempered by an injury to Josh King that is set to sideline the Norwegian international for a few weeks.
The wide-man sustained a hamstring injury in Saturday's win over Blackpool with scans revealing a tear.
"Josh King is going to be out for a few weeks with a hamstring injury," confirmed Bowyer.
"He had a scan during the week and that showed a tear so he'll be out for a while. We'll work hard to get him fit."
Tommy Spurr needed stitches in a head wound but is fit to play, the defender will wear a protective bandage at the Riverside.
Tickets for Saturday's match will go off sale at Ewood at 4pm on Friday. After that tickets will be on sale at Middlesbrough from the away ticket office from 1.30pm on the day of the game, cash only.
Prices are £27 Adults, £17 Seniors and £14 for Under 18s.