Best missed last week's game at Sheffield Wednesday with a slight calf injury but has returned to training this week and could be considered.
Also back in training is Markus Olsson after the Swedish international recovered from a hamstring strain.
Speaking ahead of Saturday's Ewood encounter, Bowyer said: "The ones that have been out for a while like Josh King and Colin Kazim-Richards are getting stronger day by day.
'We've also been boosted this week by the return of Leon Best and Markus Olsson joining in training.
"We still have one or two that are still a way from returning but we are focusing on the ones that can affect the game on Saturday."
Tickets for Saturday's match are on open sale and will be available up until the 3.00pm kick-off. Prices are from £19 for Adults, £12 for Seniors and £7 for Juniors under 16.
Book online today at www.onerovers.co.uk
and collect your tickets from the Blackburn End collection point on the day of the game.