Fabrice Muamba and Ledley King will be the special guests at Wembley Stadium to make the draw, which will be shown live on ITV1 at approximately 2.40pm.
Ties will take place over the weekend of January 5th/6th 2013.
Rovers failed to make it past the third round stage last season after losing 2-1 away to Newcastle United in an all-Premier League clash at St. James' Park.