The Rovers boss knows that for his side to triumph at Turf Moor, keeping 11 men on the pitch is of paramount importance.
"I think it is important that we keep 11 players on the pitch, that is for sure," said Bowyer.
"You could look at last year's game where Burnley were winning 1-0 and then the lad gets sent off, does that cost them in the end in the last minute? I don't know.
"But it is important that we have 11 players on the pitch."
Tickets are no longer on sale for the game but fans can watch the match in Blues Bar, or listen online via Rovers Player