Rovers go into the game at Oakwell looking to halt a run of results that has seen the Lancashire club claim just one win out of their last ten league outings.
Speaking after Wednesday's Boxing Day defeat to Middlesbrough, Murphy said: "For me it is now the biggest game of the season so far.
"I think it is massively important for us as a team to make sure that we stop the rot.
"If that means a brilliant performance and a good win, I'll take it. If it means a crap performance and a good result, I'll take that as well.
"We are halfway, we still have a chance to redeem ourselves, we've seen it with what Reading did last year .
"It is going to take a huge effort, we know that now because we're chasing, but the quality is there in the dressing room, it is a good group, everyone is trying.
"It is down to us to put it right, it is about us as players to stand up and be counted. We can't keep talking a good game, we have to play it.
"It is about stopping the defeats, getting back to some good defensive play, getting some clean sheets and scoring some goals and winning some games.
"Making sure that we turn the results round and not worry too much about where we are in the table.
"Lets get some results on the board and look where we are in a couple of weeks.
"We are fortunate that we have got two or three games in quick succession, but we are only fortunate if we get some results.
"We need to get confidence from one result and I feel that one result isn't far away. Football is a thin line, we've got to do better and there is only one way to do that is to work damn hard and to produce better quality than we have been."
Tickets for Saturday's game go off sale at Ewood this Friday. Matchday prices at Oakwell are £28 for Adults, £18 for Seniors, Juniors and Students.